Found 11 matching trials
A Study of XL765 (SAR245409) in Combination With Temozolomide With and Without Radiation in Adults With Malignant Gliomas PHASE1 The purpose of this study is to determine the safety and tolerability of XL...
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Investigational Site Number
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Open Label Treatment Extension Study With SAR245408 or SAR245409 as a Monotherapy or as a Combination Regimen PHASE1 Primary Objective:
The purpose of this study was to determine the long ter...
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Investigational Site Number 840010
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Study of the Safety and Pharmacokinetics of XL765 (SAR245409) in Adults With Solid Tumors PHASE1 The purpose of this study is to determine the safety and tolerability of XL...
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Investigational Site Number 1302
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Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors PHASE1 This research trial is testing a combination of two experimental drugs, MSC...
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Pinnacle Oncology Hematology
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Study of XL147 (SAR245408) or XL765 (SAR245409) in Combination With Letrozole in Subjects With Breast Cancer PHASE1 Phase 1 of this study will evaluate the maximum tolerated dose (MTD) of XL1...
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Investigational Site Number 1537
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Safety Study of XL765 (SAR245409) in Combination With Erlotinib in Adults With Solid Tumors PHASE1 The purpose of this study is to evaluate the safety and tolerability of XL7...
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Investigational Site Number 168983
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Trial of Pimasertib With SAR245409 or Placebo in Ovarian Cancer PHASE2 This is a double blind, randomized, placebo-controlled, 2-arm, Phase 2 tria...
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A Study of the Safety and Pharmacokinetics of SAR245409 Tablets in Patients With Solid Tumors or Lymphoma PHASE1 Primary Objective:
\- To evaluate the safety and tolerability of SAR245409...
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Investigational Site Number 840001
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A Study of Investigational SAR245409 in Patients With Certain Lymphoma or Leukemia PHASE2 Primary Objective:
\- To evaluate the efficacy of SAR245409 as determined ...
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Investigational Site Number 840012
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Study Combining SAR245409 With Rituximab or Bendamustine Plus Rituximab in Patients With Indolent Lymphoma, Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia PHASE1 Primary Objective:
\- To determine the maximum tolerated dose (MTD) and re...
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Investigational Site Number 840004
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